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A newly identified coronavirus variant, detected in recent weeks, is contributing to fluctuating infection rates globally, said Dr. Petros Karagiannis in a recent interview with Sigma's 'Protoselido' (Front Page) TV program.
This variant is distinguished primarily by an unusually severe sore throat, often accompanied by hoarseness. Other common symptoms, such as fever, runny nose, and general fatigue, remain similar to those seen in previous strains.
Dr. Karagiannis explained that these variants involve minor changes, one or two amino acids, in the viral protein responsible for entering human cells. These subtle mutations can enhance the virus’s ability to spread, though current evidence suggests symptoms are generally milder than those caused by earlier strains like Delta, which was notably more lethal.
He cautioned, however, that waning immunity over time, especially in unvaccinated individuals or those without recent infections, could lead to more pronounced symptoms. Genetic factors may also influence the severity of illness. The virus continues to pose a serious risk to people with pre-existing health conditions, as coronavirus-related deaths remain a global concern.
Regarding preventive measures, Dr. Karagiannis noted that many people continue to practice caution in crowded spaces and during travel. He observed widespread mask usage during a recent trip to London, including in airports, public transport, and shops.
Influenza vaccination rates remain low, which could contribute to more severe respiratory symptoms this season. Conversely, individuals who have received COVID-19 vaccines or have recovered from prior infections benefit from immune memory, improving their ability to fight the virus.
As winter approaches in the northern hemisphere, respiratory infections are expected to rise, a trend already seen in southern hemisphere countries such as Australia.
Dr. Karagiannis urged the public to maintain basic hygiene and protective practices—handwashing, mask-wearing, and avoiding crowded areas—noting that these precautions help protect against coronavirus as well as other respiratory viruses.
